Evaluation of Strong Ion Gap in Patients with Acute Respiratory Failure

VernacularTitle:强离子隙在急性呼吸衰竭中的应用研究
Author: Zhongyuan ZHANG ; Tao ZHANG
Publication Type:Journal Article
Keywords: Acute respiratory failure; Blood gas analysis; Strong ion gap ( SIG); Anion gap; ROC curve
From: Journal of Medical Research 2015;44(10):64-69,82
CountryChina
Language:Chinese
Abstract: Objective To evaluate the probability that strong ion gap was selected as predictive factor of mortality in patients with a -cute respiratory failure.Methods SIG was calculated with the Stewart -Figge model, after determination of blood gas ,blood pH,serum electrolytes.Results ①The incidence of acute respiratory distress syndrome and source pulmonary edema was 26% respectively in pa-tients with ARF.②There was a significant difference in the values of K +、Cl-、HCO3-、AG、pH、ALB、SIG、Cr,lactic acid,PaCO2 and PaO2 between group T 1 and control .However , there was no significant difference between recovery group T 2 and control .③There was a signifi-cant difference in the value of AG and SIG between the recovery group T 1 and death group T 1 from the patients with ARF .④SIG was a better predictor than AG by the evaluation of ROC curve .Conclusions AG and SIG can reflect the worse condition of acid -base disturb-ance in patients with ARF sensitively at the first beginning .Meanwhile , SIG may be served as a predictor for risk of mortality in patients with ARF better than AG .