Signaling pathways regulating autophagy after cerebral ischemia
10.3760/cma.j.issn.1673-4165.2015.09.014
- VernacularTitle:脑缺血后自噬调控的信号通路
- Author:
Fanna MENG
;
Yanhong DONG
- Publication Type:Journal Article
- Keywords:
Brain Ischemia;
Autophagy;
Signal Transduction;
AMP-Activated Protein Kinases;
TOR Serine-Threonine Kinases;
NF-κB;
NF-κB p50 Subunit;
Genes,p53;
Hypoxia-Inducible Factor 1
- From:
International Journal of Cerebrovascular Diseases
2015;(9):715-719,720
- CountryChina
- Language:Chinese
-
Abstract:
A lot of evidence shows that autophagy is involved in the occurrence and development of cerebral ischemia - reperfusion. Autophagy and its related signal transduction pathways may be an effective therapeutic target for ischemic brain injury. This article reviews related signal transduction pathways of autophagy regulation after cerebral ischemia.