Clinical significance of serum parameters detection in the diagnosis of hypertension disorders complicating pregnancy
10.3969/j.issn.1673-4130.2015.21.013
- VernacularTitle:妊娠期高血压病患者血清多指标检测的临床意义
- Author:
Qiang ZHENG
;
Shiping LIU
;
Li GOU
;
Xun WANG
;
Fan WANG
- Publication Type:Journal Article
- Keywords:
hypertension disorders complicating pregnancy;
calcium ion;
C-reaction protein;
uric acid;
homocysteine;
complement
- From:
International Journal of Laboratory Medicine
2015;(21):3110-3111,3114
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the diagnostic value of combined detection of serum calcium ion (Ca2+ ) ,C‐reaction protein (CRP) ,uric acid(UA) ,homocysteine(Hcy) and complement C3 ,C4 in hypertension disorders complicating pregnancy(HDCP) . Methods Patients with HDCP were enrolled as HDCP group ,and pregnant women without HDCP were enrolled as control group . Serum parameters ,mentioned above ,were detected and compared between the two groups .Diagnostic performance of the parameters was also analyzed .Results Serum levels of Ca2+ ,CRP ,UA ,Hcy and complement C3 ,C4 in HDCP group were significantly differ‐ent from those in control group(P<0 .05) .Sensitivity ,coincidence rate and correct diagnosis rate of combined detection of these six parameters were higher than single detection(P<0 .05) ,but the specificity was without significant difference(P>0 .05) .Serum lev‐els of CRP ,UA and Hcy increased with the progress of HDCP disease condition ,but serum levels of Ca2+ ,C3 and C4 decreased .Be‐tween different sub‐group of HDCP patients ,serum levels of the six parameters were with significant differences(P<0 .05) .Conclu‐sion Early combined detection of serum Ca2+ ,CRP ,UA ,Hcy and complement C3 ,C4 could be with significance for the early diag‐nosis and treatment of HDCP ,and also for the condition assessment of HDCP .
