KCa3.1 ion channels and asthma
10.3760/cma.j.issn.1673-4408.2015.05.013
- VernacularTitle:KCa 3.1离子通道与支气管哮喘
- Author:
Miao LI
- Publication Type:Journal Article
- Keywords:
Ion channel;
Asthma;
Antagonist
- From:
International Journal of Pediatrics
2015;42(5):531-533,537
- CountryChina
- Language:Chinese
-
Abstract:
Asthma is a chronic airway inflammation involved by a variety of cells.Glucocorticoid can relieve most of asthmatic patient's symptom,but cannot treat all patients with asthma.KCa3.1 ion channel expressed in a variety of immune cell surface, participate in a variety of autoimmune disease immune process.Because potassium-calcium ion channels are involved in the immune process mediated by T lymphocytes, the adjustment of the function of KCa3.1ion channels may be a new way for asthma treatment.
