Comparison of therapeutic effect between PCI and intravenous administration thrombolysis on aged pa-tients with acute myocardial infarction
10.3969/j.issn.1008-0074.2015.06.20
- VernacularTitle:老年急性心肌梗死患者 PCI 与经静脉给药溶栓疗效的比较
- Author:
Yanhong CUI
- Publication Type:Journal Article
- Keywords:
Myocardial infarction;
Angioplasty,balloon,coronary;
Thrombolytic therapy
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2015;24(6):653-655,656
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare therapeutic effect of percutaneous coronary intervention (PCI ) and intravenous administration thrombolysis on aged patients with acute myocardial infarction (AMI) .Methods :A total of 180 aged AMI patients were randomly and equally divided into PCI group and intravenous thrombolysis group (IVT group) . Recanalization rate of infarct‐related artery (IRA) ,left ventricular ejection fraction (LVEF) during hospitalization and follow‐up ,and incidence rate of major adverse cardiovascular events (MACE ) were compared between two groups .Results:Compared with IVT group ,there was significant rise in recanalization rate of IRA (61.1% vs . 92.2% ) ,significant improvement in LVEF at the end of treatment [ (52.26 ± 7.33)% vs . (58.27 ± 7.59)% ,and during follow‐up [on three‐month follow‐up: (53.59 ± 8.04)% vs . (60.44 ± 7.53)% ,on 12‐month follow‐up:(55.16 ± 7.35)% vs .(63.71 ± 7.77)% ] ,and significant reduction in total incidence rate of MACE after 12‐month follow‐up (82.22% vs .24.44% ) in PCI group ,P<0.01 all .Conclusion:Compared with intravenous administration thrombolysis ,the recanalization rate of infarct‐related artery more high ,cardiac function recovers more faster , MACE much less in PCI group ,so PCI can be regarded as a preferred therapeutic plan for aged AMI .
