A Case of Wound Infection Caused by Staphylococcus aureus with Decreased Susceptibility to Teicoplanin.
- Author:
Yeon Joon PARK
1
;
Myungshin KIM
;
Byung Kee KIM
;
Sun Moo KIM
;
Sang In SHIM
Author Information
1. Department of Clinical Pathology, Catholic University of Korea, College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Staphylococcus aureus;
Teicoplanin;
Rifampin
- MeSH:
Agar;
Diffusion;
Glycopeptides;
Methicillin Resistance;
Rifampin;
Staphylococcus aureus*;
Staphylococcus*;
Teicoplanin*;
Wound Infection*;
Wounds and Injuries*
- From:Korean Journal of Clinical Pathology
1998;18(3):396-398
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
With increased infection by methicillin-resistant staphylococci, the use of glycopeptides has been increasing. Recently, staphylococci with decreased susceptibility to glycopeptides, especially teicoplanin, are increasingly reported. We isolated a Staphylococcus aureus strain isolated repeatedly from a wound culture, which showed susceptibility to teicoplanin by the disk diffusion method but showed growth on the Mueller-Hinton agar containing 6 g/mL of teicoplanin. This strain was clinically resistant to treatment at 200 mg/day of teicoplanin. By changing the treatment into combining rifampin (600 mg/day) and increasing the dose of teicoplanin (400 mg/day), the S. aureus was not isolated any more.
