Investigation on T-lymphocyte subsets absolute counting and CD4+/CD8+ratio in healthy adults of Ugyur and Han nationalities in Karamy
10.3969/j.issn.1673-4130.2015.22.003
- VernacularTitle:克拉玛依地区维吾尔族和汉族健康成人T 淋巴细胞亚群绝对计数及CD4+/CD8+比值研究
- Author:
Qin FENG
;
Gang DU
;
Guiying YANG
;
Lijuan ZHANG
;
Xinrong YUAN
;
Shanjun ZHU
- Publication Type:Journal Article
- Keywords:
CD3+;
CD4+;
CD4+ /CD8+ ratio;
Ugyur nationality;
Han nationality
- From:
International Journal of Laboratory Medicine
2015;(22):3227-3228,3231
- CountryChina
- Language:Chinese
-
Abstract:
Objective To built the reference range of peripheral blood T-lymphocyte subsets including CD3+ ,CD4+ ,CD8+ and CD4+ /CD8+ ratio in healthy adults of Ugyur and Han nationalities and to provide basis for the diagnosis ,therapy and prognosis of disease .Methods A total of 181 blood samples were collected from healthy adults .The cell chip quantitative detection technology was used to detect CD3+ ,CD4+ and CD8+ ,CD3+ ,CD4+ absolute value ,CD8+ and CD4+ /CD8+ ratio were compared between Ugyur and Han nationalities .Results CD8+ absolute counting and CD4+ /CD8+ ratio had no significant difference between Ugyur and Han nationalities(P>0 .05) ,while the CD3+ ,CD4+ absolute counting had significant difference(P<0 .05) .Conclusion The discrepancy of territory and living environment should be taken into account for building a reference values of CD4+ .