Research of platelets activation during Inflammation
10.11958/j.issn.0253-9896.2015.10.033
- VernacularTitle:血小板在炎性疾病中活化机制研究进展
- Author:
Yuzhi LIU
;
Jianlong MEN
- Publication Type:Journal Article
- Keywords:
platelet activation;
inflammation;
sepsis;
fungi;
asthma;
review
- From:
Tianjin Medical Journal
2015;(10):1209-1212,1213
- CountryChina
- Language:Chinese
-
Abstract:
Platelets is the important hemostatic component in the blood and the critical participants in inflammation. It is an important promoting factor during inflammation and can recruit leukocytes and aggregate in sepsis. Decreasing plate?let count was correlated with reverse clinical outcome. Therefore, the value of the platelets examination in clinical monitor was studied by many researchers. Under circumstance of fungal infections, platelets mediate antimicrobial activity and assist dissemination of the fungi synchronously. Regulating interaction between platelets and fungi is difficult. In allergic inflamma?tion patients, the excessive activating of platelets aggravates airway obstruction and worsen pulmonary function. We reviewed current research in activating platelets during inflammation.
