Optimizing ethanol extraction technology for no sugar runfei granules by orthogonal experiment design
- VernacularTitle:正交试验优选无糖润肺颗粒醇提取工艺
- Author:
Lijuan SHEN
;
Xingji YANG
;
Jing DU
;
Yan HE
;
Yinghua FU
- Publication Type:Journal Article
- Keywords:
no sugar runfei granules;
ethanol extraction technology optimization;
orthogonal experiment;
baicalin
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;(9):158-160,163
- CountryChina
- Language:Chinese
-
Abstract:
Objective To optimize ethonal extraction technology for no sugar runfei granules.Methods Ethanol was used as a solvent to extract the ethanol dissolvable ingredients in 9 kinds of medicinal materials.The formula L9 (34 ) table was used to examine the effects of 4 factors and 3 levels.The weighted sum of baicalin content and the dried extract quantity was used as quantitative index.Results The maximize optimize condition for extraction of ethanol dissolvable ingredients was as follows:9 kinds of medicinal materials, add of 10-fold 70% ethanol solution, soaked for 45 min, and extracted by heating reflux for 3 times,1.5 h each time.Conclusion The method can maximize extraction of ethanol dissolvable effective ingredents in 9 kinds of medicinal materials and can be used as ethonal extraction technologgary of no sugar runfei granules.
