Correlation study of endothelial growth factor receptor transportation with tumor treatment
10.11958/j.issn.0253-9896.2015.08.030
- VernacularTitle:表皮生长因子受体运输与肿瘤治疗的研究进展
- Author:
Lu CHEN
;
Chao TAN
- Publication Type:Journal Article
- Keywords:
receptor,epidermal growth factor;
signal transduction;
oncogenes;
antineoplastic protocols;
review
- From:
Tianjin Medical Journal
2015;(8):939-941,942
- CountryChina
- Language:Chinese
-
Abstract:
Abnormal endothelial growth factor receptor transportion was involved in the development of tumor so more and more researches focus it as a target of anti-tumor therapy. Based on the known mechanism in EGFR mis-localization this review summarized the latest research progress in the abnormality in signal of EGFR transportation and its role in tumori?genesis, anti-tumor drug and therapy that target to EGFR. It is aim to provide reference for the development of anti-tumor treatments which target EGFR and for the mechanism in resistance of anti-tumor.
