Correlation between N-terminal pro B type natriuretic peptide and cystatin C content in Kazak patients with hypertensive heart disease
10.3969/j.issn.1008-0074.2015.05.17
- VernacularTitle:哈萨克族高血压性心脏病 N-端脑利钠肽前体与胱抑素 C含量的相关性
- Author:
Gang YAO
;
Gang WU
;
Haifeng SONG
;
Yanqun WANG
- Publication Type:Journal Article
- Keywords:
Natriuretic peptide,brain;
Cystatin C;
Heart failure
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2015;24(5):530-533,533
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To deteat N‐terminal pro B type natriuretic peptide (NT‐pro BNP) and cystatin C (Cys C) con‐tent in Kazak patients with hypertensive heart disease (HHD) complicated heart failure (HF) and analyze the corre‐lation between them .Methods :A total of 100 Kazak HHD patients were divided into hypertension complicated HF group (Complicated HF group , n=50) and pure HHD group (n=50) .Venous blood sample was taken within 24h after hospitalization for measuring serum levels of NT‐proBNP and Cys C ,then they were compared and analyzed between two groups .Results:Compared with pure HHD group ,there were significant rise in serum levels of NT‐proBNP [ (246.53 ± 165.65) ng/L vs .(4568.32 ± 2722.36) ng/L] and Cys C [ (0.82 ± 0.31) mg/L vs .(1.93 ± 2.46) mg/L] in complicated HF group , P< 0.01 both .Spearman correlation analysis indicated that serum NT‐proBNP level was positively correlated with Cys C level in complicated HF group , r=0.961 , P<0.01. Conclusion:In Kazak patients with hypertensive heart disease complicated HF ,serum NT‐proBNP and Cys C levels significantly rise and they significantly positively correlate ,so it suggest there may be slight damaged renal function also .
