Clinical Efficacy of CAG Regimen Used in 35 Cases of Newly Diagnosed Acute Myeloid Leukemia in Elder-ly Patients
- VernacularTitle:CAG方案治疗35例老年初治急性髓性细胞白血病的疗效观察
- Author:
Lingling GUO
;
Yongwei HONG
- Publication Type:Journal Article
- Keywords:
CAG regimen;
Acute myeloid leukemia;
Elderly patients;
Efficacy
- From:
China Pharmacist
2015;(8):1366-1367,1368
- CountryChina
- Language:Chinese
-
Abstract:
To study the efficacy of CAG regimen used in 35 cases of newly diagnosed acute myeloid leukemia in elder-ly patients. Methods:Totally 35 cases of elderly patients with acute myeloid leukemia were randomly divided into two groups. The pa-tients in the control group (15 cases) were treated with standard chemotherapy treatment, while the CAG regimen group (20 cases) was treated with CAG regimen (cytarabine, aclarubicin and granulocyte colony-stimulating factor). After one treatment course, the chemotherapy efficacy was observed, and the neutrophil and platelet recovery time and the incidence of adverse reactions in the two groups were compared. Results:The treatment efficacy of the CAG regimen group was 90%, which was higher than that of the control group (60%, P<0. 05). The neutrophil and platelet recovery time of the CAG regimen group was significantly shorter than that of the control group (P<0. 05). The incidence of adverse reactions in CAG regimen group was much lower than that of the control group(P<0. 05). Conclusion:The efficacy of CAG regimen used in the 35 cases of newly diagnosed acute myeloid leukemia in elderly pa-tients is promising, which can effectively control the progression of the disease and accelerate blood cell recovery with high safety.
