The effect of combination mode of blood purification on insulin resistance in MODS patients
10.3969/j.issn.1671-8348.2015.23.011
- VernacularTitle:组合式血液净化模式对 MODS 患者胰岛素抵抗的影响?
- Author:
Dexing YANG
;
Mian XU
;
Yuexin YAN
;
Chuanyun QIAN
;
Rong LIU
- Publication Type:Journal Article
- Keywords:
hemofiltration;
plasma exchange;
insulin resistance;
bilirubin
- From:
Chongqing Medicine
2015;(23):3204-3205,3209
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of combination mode of blood purification on insulin resistance in MODS patients and discuss the best mode of blood purification to improve insulin resistance in MODS patients.Methods A total of 60 MODS pa-tients were selected and randomly divided into control group(single mode of blood purification)and treatment group(combination mode of blood purification),each group of 30 cases.Blood glucose (BG),glucose standard deviation (BGSD),coefficient of variation of blood glucose (BGCV),regular insulin dosage (Ins),fasting insulin (FINS),insulin resistance index (HOMA-IR),HbA1c,C-re-active protein (CRP)was observed before and after treatment.Results BG,HbA1c,FINS,CRP,HOMA-IR,Ins of experimental group was lower than that of control group (P <0.05).After treatment,BG,FINS,CRP,HOMA-IR,Ins was declined in experi-mental group (P <0.05).After treatment,HbA1c was not changed in experimental group (P >0.05 ).Conclusion Combination mode blood purification may be more effective to insulin resistance in MODS patients.
