Synthesis of some derivatives with biological properties of 2-amino-4,6-dimethyl-pirimidine
- Author:
Tran -- Minh
- Publication Type:Journal Article
- Keywords:
2-amino-4,6-dimethyl-pirimidine
- MeSH:
Biological Products;
chemistry;
pharmacy
- From:Pharmaceutical Journal
2003;327(7):15-16
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
The 2- hydroxy-4,6-dimethyl pyrimidine (8),2-amino-4,6 –dimethyl pyrimidine (10) and sulfamet-hazine(1)were prepared by condensation of urea (4), guanidine (5) or sulfaguanidine (6) with acetylacetone(7) and then the 2-chloro-4,6-dimethyl pyrimidine (9) was obtained by treating the compound (8) with phosphorylchoride (POCl3)
