The lipid Metabolism of Zhibitai in liver dysfunction
10.3760/cma.j.issn.1008-6706.2015.16.023
- VernacularTitle:脂必泰对肝功能损害患者血脂水平的影响
- Author:
Lingyun CHEN
;
Ming CHEN
- Publication Type:Journal Article
- Keywords:
Liver damage;
Zhibitai;
Lipid;
Atorvastatin
- From:
Chinese Journal of Primary Medicine and Pharmacy
2015;(16):2473-2474,2475
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the lipid levels in liver damage.Methods 82 patients with liver damage were divided into the study group(41 patients)and control group(41 patients),the control group patients were given treatment of atorvastatin,while the study group patients were given treatment of Zhibitai,the lipid metabolism of the two groups were compared.Results In the study group,levels of TC (5.16 ±0.8)mmol/L,TG(1.90 ±0.08)mmol/L,LDL(2.03 ±0.11)mmol/L were significantly lower than before treatment TC(5.82 ±1.26)mmol/L (t =4.38, P <0.05),TG(2.16 ±0.85)mmol/L (t =6.37,P <0.05),LDL(3.67 ±0.09)mmol/L (t =6.42).The HDL level (1.39 ±0.26)mmol/L was significantly increased (0.86 ±0.21)mmol/L (t =7.52,P <0.05)after 4 weeks treat-ment(P <0.05).The incidence of adverse events in the study group (7.3%)was significantly lower than the control group (17.1%)(P <0.05).Conclusion Zhibitai is safe and effective with use value in the treatment of liver dys-function.
