Escaping mechanism from innate immunity mediated clearance by high pathogenic influenza virus during infection
10.3969/j.issn.1000-484X.2015.09.001
- VernacularTitle:高致病性流感病毒逃逸宿主固有免疫清除作用的机制
- Author:
Jianqing XU
- Publication Type:Journal Article
- Keywords:
High pathogenic influenza;
Innate immune response;
Immune escape;
Type Ⅰinterferon;
Hypercytokinemia
- From:
Chinese Journal of Immunology
2015;(9):1153-1155,1162
- CountryChina
- Language:Chinese
-
Abstract:
Severe influenza infection is usually associated with hypercytokinemia ,but the type Ⅰ Interferon remains at low lever or absence.The regulatory mechanism on or the immune escaping mechanism from type I interferon by virus remains to be deter -mined.We briefly summarized the progress in this field and raise several questions to be addressed in the future .
