Research progress of the relationship between autophagy andβ-amyloid peptide in Alzheimer’ s diseese
10.3969/j.issn.1671.7856.2015.008.014
- VernacularTitle:阿尔茨海默病：自噬与β淀粉样肽关系的研究进展
- Author:
He JIN
;
Rong WANG
- Publication Type:Journal Article
- Keywords:
Alzheimer’s disease;
β-peptide amyloid;
Autophagy
- From:
Chinese Journal of Comparative Medicine
2015;(8):68-71,75
- CountryChina
- Language:Chinese
-
Abstract:
Autophagy is an important pathway in the body to remove damaged cell organelles and dysfunctional proteins to maintain protein equilibrium and intracellular homeostasis by the lysosomal system .As a degenerative disease of central nervous system , the main feature of Alzheimer ’ s disease is abnormal protein aggregation .However , the role of autophagy in the pathogenesis of Alzheimer ’ s disease is not fully clear yet .The aim of this paper is to take β-amyloid peptide as a starting point to explore the relationship between autophagy and β-amyloid peptide in the pathogenesis of Alzheimer’s disease.
