Effects of tirofiban combined with nitroprusside injection through the rapid exchange balloon catheter on no-reflow phenomenon during elective PCI
10.3969/j.issn.1671-8348.2015.22.008
- VernacularTitle:经快速交换球囊导管注射替罗非班联合硝普钠对择期PCI 术中无复流的作用
- Author:
Jun XIAO
;
Jun LI
;
Ruihua YUE
;
Junle SHEN
;
Ying ZHANG
- Publication Type:Journal Article
- Keywords:
no-reflow phenomenon;
coronary vessels;
nitroprusside;
balloon catheter;
tirofiban
- From:
Chongqing Medicine
2015;(22):3048-3049,3052
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of tirofiban combined with nitroprusside injection through the rapid exchange balloon catheter with self-made side holes on no-reflow (NR)phenomenon during elective percutaneous coronary intervention (PCI).Methods A total of 49 patients with NR phenomenon were randomly divided into the balloon catheter group (n=25)and the guiding catheter group (n=24).Tirofiban combined with nitroprusside were used in both groups.Thrombolysis in myocardial infarction (TIMI)grade and corrected TIMI frame count (CTFC)of target coronary artery at 10 minutes after administration were assessed.Results At 10 minutes after drugs injection,there were 21 (84.0%)patients with target of coronary TIMI 3 grade in the balloon catheter group,and 13 (54.2%)patients in the guiding catheter group.The CTFC was (33.5±12.5)frame in the balloon catheter group,and (41.9±1 5.3)frame in the guiding catheter group.The difference in TIMI and CTFC between the two groups was significantly (P <0.05).Conclusion Injection tirofiban combined with nitroprusside through the rapid exchange balloon cathe-ter with self-made side holes in NR patients during elective PCI might be feasible and effective.
