Quality Management of Fluorescence in Situ Hybridization Methods for Clinical Laboratories
10.3969/j.issn.1671-7414.2015.02.048
- VernacularTitle:临床实验室荧光原位杂交技术的质量管理
- Author:
Yang FEI
;
Wei WANG
;
Zhiguo WANG
- Publication Type:Journal Article
- Keywords:
cytogenetics;
fluorescence in situ hybridization;
quality management
- From:
Journal of Modern Laboratory Medicine
2015;(2):149-151,155
- CountryChina
- Language:Chinese
-
Abstract:
FISH technology has become a routine technique in many clinical laboratories.It can be used for the examination of genetic aberrations that are too small to visualize by conventional cytogenetic assays,but too large to detect by standard DNA sequencing.Today,FISH applications are used not only in medical genetics,but also in many other disciplines including neuroscience,evolutionary biology,microbiology,pathology,toxicology,and reproductive genetics.As FISH technology keep developing,the requirement of the results of FISH is increasingly high.This paper described the quality management for FISH detailedly,aimed at improving the accuracy and reliability of the result of FISH,satisfying the requirements of clini-cians and patients and improving the healthcare quality and outcome of patients,hoping for providing some references for la-boratories who develop FISH technology.
