Relationship between Homocysteine,Glycosylated Hemoglobin, Lipids and Posterior Circulation Ischemia
10.3969/j.issn.1671-7414.2015.02.041
- VernacularTitle:同型半胱氨酸、糖化血红蛋白和血脂与后循环缺血的相关性研究
- Author:
Youjian LI
;
Guilan GU
;
Zhiyong WANG
;
Feng WANG
;
Cancan JIN
- Publication Type:Journal Article
- Keywords:
homocysteine;
glycosylated hemoglobin;
lipids;
posterior circulation ischemia
- From:
Journal of Modern Laboratory Medicine
2015;(2):132-133,136
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between homocysteine(HCY),glycosylated hemoglobin(HbA1c),lipids and posterior circulation ischemia and the clinical significance of their levels in the posterior circulation ischemic (PCI)diseases. Methods Difference between PCI were diagnosed in 140 examinees and a healthy control group,with fasting serum,HCY, HbA1c,total cholesterol (TC),triglyceride (TG),high density lipoprotein cholesterol (HDL-C)and low-density lipoprotein cholesterol (LDL-C)were detected.Results HCY and HbA1c were significantly higher,HDL-C was significantly lower in the patients with PCI,two independent sample t-test showed a significant difference between the test group and control group (P <0.001 and P =0.001),the remaining lipid indicators was not statistically significant.Spearman rank correlation analysis showed that HCY levels had significant positive correlation (P <0.001)and TG levels had significant negative cor-relation (P =0.013)with the subjects age,HCY levels had significant negative correlation with TG levels(P = 0.028), HbA1c levels had significant positive correlation with TG levels and LDL-C levels(P =0.001 and P =0.027).Conclusion High levels of HCY and HbA1c were closely associated with PCI,which HCY and HbA1c should be attached great impor-tance to the effective prevention and treatment and improve of PCI.
