Clinical Significance of Detecting the Levels of Homocysteine, Combined with Lipoprotein(a)and High Sensitivity C-reaction Protein in Serum from Patients with Diabetes Mellitus
10.3969/j.issn.1671-7414.2014.06.048
- VernacularTitle:糖尿病患者血清同型半胱氨酸、脂蛋白a、超敏C反应蛋白联合检测的临床意义
- Author:
Lin LI
;
Huan TU
;
Wu ZHU
;
Weihong CHEN
;
Hua WANG
;
Jianjun SHEN
- Publication Type:Journal Article
- Keywords:
diabetes;
homocysteine;
apolipoprotein a;
high sensitivity C reactive protein
- From:
Journal of Modern Laboratory Medicine
2014;(6):148-149,152
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical significance of detecting the levels of homocysteine,lipoprotein(a)and high sensi-tivity C-reaction protein in serum from patients with diabetes mellitus.Methods Serum Hcy,Lp(a)and hsCRP levels were detected from 30 patients of diabetes mellitus with microangiopathy,and 30 patients of simple diabetic,45 heslthy individuals as normal controls,all the data were analysed by SPSS13.0 software.Results The levels of Hcy,Lp(a)and hsCRP in dia-betes mellitus with microangiopathy group were higher than that of normal controls and simple diabetic group.In all groups, the positive rate of Lp(a)was highest (P<0.05).Detecting the serun Hcy combined with Lp(a)and hsCRP had higher positive rate then single detecting (P<0.05).Conclusion The generation and development of diabetes mellitus were corre-lated with the serum levels of Hcy,Lp(a)and hsCRP.Detecting the serum Hcy combined with Lp(a)and hsCRP have more clinical significance than single detecting.Serum Hcy,Lp(a)and hsCRP level has the remarkable significance to diagnosis and prediction diabetes mellitus with microangiopathy.
