Analysis of Clinical Distribution and Drug-resistance of Pathogen in Urinary Tract Infection in Wuhan

VernacularTitle:武汉地区泌尿道感染病原菌的分布及耐药性分析
Author: Zhen LI ; Congrong LI ; Xuan CAI ; Juan LI ; Qing WU ; Ziqi HE
Publication Type:Journal Article
Keywords: urinary tract infection; urine culture; pathogen; drug resistance
From: Journal of Modern Laboratory Medicine 2014;(5):135-137,140
CountryChina
Language:Chinese
Abstract: Objective To investigate the tendency of distribution and drug-resistance of the causative organisms of urinary tract infections(UTIs)in Wuhan,and provide reliable evidence for clinical treatment.Methods Analyzed the 5 378 stains of pathogen isolated from the urine of patients in hospital.The bacteria isolates were identified with BD Phoenix-100 while can-dida isolates were identified by color plate.Results A total of 5 378 stains of pathogen had been isolated.There were 2 945 stains (54.8%)of Gram-negative bacteria,1 657 stains (30.8%)of Gram-positive bacteria,776 stains (14.4%)of fungus. The rates of Escherichiacoli resistant to penicillin were highest (>83%),and there were no carbapenem-resistant strains. There were vancomycin and linezolid-resistant Enterococcispp strains,the lowest dection rates of which were 0.3%.The de-tection rate of MRCNS was over 83%.Conclusion Escherichiacoli was the most common pathogens of urinary tract infec-tion,and theβ-lactamase inhibitor complex can be used as empirical treatment of E.coli infections.Thedetection rate of MRCNS increased,which shoud be kept a watchful eye on.