Surveillance of Antimicrobial Resistance and Pathogen of Clinical Isolates in Hebei Province in 2 0 1 2
10.3969/j.issn.1671-7414.2014.05.010
- VernacularTitle:2012年河北地区临床分离细菌分布及耐药性监测
- Author:
Dongyan SHI
;
Jianhong ZHAO
;
Jihong LI
;
Lijun CAO
;
Aiying DONG
;
Yan SUN
;
Qian WANG
;
Jianwei LIU
;
Min ZHANG
;
Wenshen ZHAO
;
Yulan CHEN
;
Yinghui GUO
;
Junhua FENG
;
Zheng ZHANG
;
Wei TIAN
;
Hui XU
;
Shujun LI
;
Shuang XIE
;
Jinlu LIU
- Publication Type:Journal Article
- Keywords:
surveillance;
pathogen;
bacterial susceptibility testing
- From:
Journal of Modern Laboratory Medicine
2014;(5):49-53,57
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate antimicrobial resistance and pathogen in hebei antibacterial resistance investigation net in 2012.Methods Antimicrobial susceptibility test was detected by Kirby-Bauer method or broth dilution test.Results were analyzed according to CLSI 2010 breakpoints.WHONET 5.5 software was used to analyze the data.Results A total of 10 504 clinical isolates were collected in 2012,of which gram negative bacilli and gram positive cocci accounted for 76.2%, 23.8%,respectively.The most common pathogen in gram-negative rod was E.coli,K.pneumoniae,P.aeruginosa, A.baumanii and E.cloacae respectively.The most common pathogen in gram-positive cocci was S.aureus,E.facium,E-.faecalis,S.pneumoniae and S.epidermidis.ESBL rate of E.coli and K.pneumoniae was 66.5 and 46.7%.The resistant rate of E.coli,K.pneumoniae,E.cloacae to imipenem was 0.1%,0.5%,8.9% and to meropenem was 0.1%,0.6%,4.2%, respectively.P.aeruginosa was resistant to imipenem and meropenem were 38.9% and 32.3%.A.baumanii was resistant to imipenem and meropenem were 5 6.5% and 5 9.7%.Methicillin-resistant strains accounted for an average of 5 7.5% in S.aureus and 87.3% in coagulase negative staphylococcus.Staphylococcus was still susceptible to minocycline and chloram-phenicol.No staphylococcal strains were found resistant to vancomycin,linezolid.But a few coagulase negative staphylococcal strains were resistant to teicoplanin.Conclusion Surveillance of antimicrobial agents played an important role in controlling hospital infection.
