Recombinant protein of Echinococcus g ranulosus EG95
10.3969/cjz.j.issn.1002-2694.2014.10.017
- VernacularTitle:棘球蚴 EG95重组蛋白研究进展
- Author:
Hongmin LI
;
Zhongzi LOU
;
Li LI
;
Zhenhua LI
;
Jianqiu LI
;
Hongbin YAN
;
Wanzhong JIA
- Publication Type:Journal Article
- Keywords:
Echinococcus granulosus;
EG95 gene;
recombinant antigen;
vaccine;
expression system;
immuno-protec-tive effect
- From:
Chinese Journal of Zoonoses
2014;(10):1066-1070,1078
- CountryChina
- Language:Chinese
-
Abstract:
Echinococcosis (hydatid disease) caused by the metacestodes of Echinococcus granulosus tapeworm is a seri-ous zoonotic infection ,which leads to a large amount of economic loss in human and animals .It needs to be prevented urgently . The EG95 protein is highly conserved and crucial for survival and development of E .granulosus in the host ,which means that it is one of the potential candidate antigens for vaccines characterized so far .Great effort has been made to construct and ex-press the recombinant EG95 (rEG95) gene in various kinds of expression systems in order to obtain an efficient defined antigen . This review will summarize research progress on expression of rEG95 in different vector systems .
