Highlights of lymphoma research: reports from the 56th American Society of Hematology annual meeting
10.3760/cma.j.issn.1009-9921.2015.01.002
- VernacularTitle:恶性淋巴瘤领域新亮点:第56届美国血液学会年会报道
- Author:
Shenmiao YANG
- Publication Type:Journal Article
- Keywords:
Lymphoma;
Programmed cell death-1;
Maintenance treatment;
Positron-emission tomography;
American Society of Hematology annual meeting
- From:
Journal of Leukemia & Lymphoma
2015;24(1):3-5,8
- CountryChina
- Language:Chinese
-
Abstract:
The top three highlights of lymphoma research in the 56th American Society of Hematology annual meeting were introduced:programmed cell death-1 (PD-1) pathway blocking which protects T cells from exhaustion and enhances the tumor surveillance achieved a high response rate in the heavily treated refractory and relapsed Hodgkin lymphoma.Maintenance of brentuximab vedotin,a conjugation of an antiCD30 monoclonal antibody and a microtubule-disrupting agent,post autologous transplantation of relapsed/refractory Hodgkin lymphoma effectively decreased the incidence of disease progression.The interim PET-CT response-adapted-protocol changing did not improve the outcome of the patients with aggressive lymphoma.
