Feasibility and safety of ketamine,propofol combined with fentanyl in anesthesia for pediatric patients
10.3760/cma.j.issn.1008-6706.2015.07.031
- VernacularTitle:氯胺酮、丙泊酚复合芬太尼用于小儿手术麻醉的可行性与安全性
- Author:
Feng SHI
- Publication Type:Journal Article
- Keywords:
Anesthesia;
Ketamine;
Propofol;
Fentanyl;
Child
- From:
Chinese Journal of Primary Medicine and Pharmacy
2015;(7):1052-1053,1054
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the safety and feasibility of ketamine,propofol compound fentanyl com-bined with fentanyl in anesthesia for pediatric patients.Methods 70 cases of children with elective pseudo operation were randomly divided into the two groups of 35 cases in each group,the control group were taken ketamine,propofol for anesthesia,while the observation group were treated with fentanyl on basis of that,the anesthesia effect and inci-dence of adverse reactions were observed and compared between the two groups.Results HR and MAP at 15min during operation and after operation of the control group were increased significantly than those before anesthesia,the difference was statistically significant(t=7.33,7.19,8.26,8.11,all P<0.05),while HR and MAP in the observa-tion group at each time point of showed no significant difference(t=1.03,1.10,1.12,2.01,all P>0.05)when compared with pre anesthesia;The postoperative awake time of the observation group was (12.54 ±2.16)min,which was significantly less than (23.54 ±6.27)min of the control group(t=7.78,P<0.05),and its intraoperative and postoperative adverse reaction rate was 11.43%,which was significantly less than 42.86%of the control group(χ2 =8.33,P<0.05).Conclusion Ketamine,propofol combined with fentanyl has a good anesthesia effect better in pedi-atric,which can be maintained stable of hemodynamics,and children can rapid recovery after operation,with fewer adverse reactions.
