Study Progress in Vaginal Mucoadhesive Drug Delivery Systems
- VernacularTitle:阴道黏膜给药系统的研究进展
- Author:
Dongdong MA
;
Qingli MENG
;
Hongmei LIU
;
Linhua WU
;
Jingling TANG
- Publication Type:Journal Article
- Keywords:
Vaginal mucoadhesive drug delivery;
Gels;
Vaginal films;
Liposomes;
üano-silver
- From:
China Pharmacist
2015;(4):649-651,697
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To review the progress in vaginal mucoadhesive drug delivery systems. Methods:Based on the recently published papers,the research on the application of vaginal mucoadhesive drug delivery systems was classified and summarized. Re-sults:Vaginal mucoadhesive drug delivery systems not only showed safety,effectiveness and strong permeability but also avoided the first pass effect,prolonged drug residence time and improved bioavailability and compliance of patients. Conclusion:Vaginal mucoad-hesive drug delivery systems are becoming research hotspots and exhibit broad application prospects to replace the traditional delivery systems.