Imaging observation of cerebral ischemia reperfusion injury after interventional therapy in acute middle cerebral artery occlusion
10.3969/j.issn.1671-8348.2015.12.001
- VernacularTitle:介入治疗大脑中动脉急性闭塞后脑缺血再灌注损伤的影像学观察
- Author:
Xu YI
;
Shusheng JIAO
;
Chengchun LIU
;
Zhihong ZHANG
;
Ya WU
;
Xiaoshu LI
;
Chunrong LIANG
;
Meng ZHANG
;
Yanjiang WANG
- Publication Type:Journal Article
- Keywords:
middle cerebral artery occlusion;
interventional therapy;
ischemia reperfusion injury;
brain edema
- From:
Chongqing Medicine
2015;44(12):1585-1587,1591
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the imaging changeof cerebral ischemireperfusion injury (CIRI) afteinterventional therapy in acute middle cerebral artery occlusion .Method32 patientwith acute middle cerebral artery occlusion in ouhospital from January 2013 to Novembe2014 were selected .16 casewere performed the recanalization therapy aftearterial thrombolysiand/omechanical thrombectomy(recanalization group) and 16 casewere notreated by thrombolytitherapy (non-recanalization group) .The differenceof brain imaging changes(onse,on 3 ,7 d afteonset) were analyzed and compared between the two group. ResultThe proportion of lateral ventricle compression degree and the shifdegree of brain midline on 3 d afteonsein the reca-nalization group were greatethan those in the non-recanalization group ,the differencebetween the two groupwere statistically significant[0 .50 ± 0 .11 v.0 .58 ± 0 .10 ,0 .57(0 .18 ,0 .83)cm v.0 .22(0 ,0 .57)cm ,P＜0 .05] ,while which on 7 d of onsein the recanalization group were lesthan those in the non-recanalization group[0 .80 ± 0 .11 v.0 .55 ± 0 .12 ,0(0 ,0 .13) v.0 .46(0 , 0 .88)cm ,P＜0 .055] .Conclusion Although the interventional therapy ian importanmeasure foearly treatmenof ischemistroke ,buiaggravatethe early brain edem,therefore CIRI induced by the interventional therapy should be paid more attention to.
