Clinicolpathologic study of 21 cases lymphoblastic lymphoma

VernacularTitle:淋巴母细胞淋巴瘤21例临床病理分析
Author: Li GUO ; Weiwei HU
Publication Type:Journal Article
Keywords: Lymphoma,lymphoblastic; Pathology,clinical
From: Journal of Leukemia & Lymphoma 2012;21(5):288-289,293
CountryChina
Language:Chinese
Abstract: ObjectiveTo investigate the clinicopathologic features of lymphoblastic lymphoma (LBL).Methods21 cases of LBL were examined by light microscopy and immunohistochemistry,and analyzed with clinical features.Results21 cases of LBL patients ranging in age from 4 to 86 years old,including 17 cases originated from the lymph nodes, the other 4 were from the nasopharynx, breast, pleura and mediastinum respectively. Histopathologically: lymphoid cells were median sized, showing a diffuse infiltration. The neoplastic cells had fine chromatin, higer nuclei mitoses. The tumors were positive for TdT and CD99.ConculsionPatients especially who have enlarged lymph nodes in adolescents favor the diagnosis of LBL.The tumor cells show a diffuse infiltration,usually with median size,fine chromatin.The positivity for TdT in immunostaining can confirm the diagnosis of LBL.