Expression of CD30 in Hodgkin lymphoma cells transfected with mtr Ⅱ gene
10.3760/cma.j.issn.1009-9921.2009.03.001
- VernacularTitle:霍奇金淋巴瘤细胞转染mtrⅡ基因后CD30表达的意义
- Author:
Yudong LIN
;
Shaohuan CAI
;
Mingyuan WANG
;
Cong CHEN
;
Jingli DU
- Publication Type:Journal Article
- Keywords:
Mtr Ⅱ gene;
Hodgkin lymphoma;
Antigens,CD30
- From:
Journal of Leukemia & Lymphoma
2009;18(3):129-130,133
- CountryChina
- Language:Chinese
-
Abstract:
Objective To approach the expression and significance of CD30 in Hodgkin lymphoma cells which were transfected with mtr Ⅱ gene. Methods The CD30 expression of Hodgkin lymphoma cells in those transfected with mtr Ⅱ gene was analysed by immunohistochemical technique respectively. Results The CD30 expression rate of Hodgkin lymphoma cells which were transfected with mtr Ⅱ gene was higher than that of Hodgkin lymphoma cells which weren't transfected with mtrⅡ gene (P ＜0.01). Conclusion The mtr Ⅱ gene may be related to the malignant transformation of Hodgkin lymphoma.
