Analysis for Usefulness of Arterial Embolization on Sacral and Pelvic Giant Cell Tumors.
10.5292/jkbjts.2013.19.2.50
- Author:
Seung Hyun KIM
1
;
Gil Sung YOON
;
Yong Jin CHO
;
Kyoo Ho SHIN
;
Jin Suck SUH
;
Woo Ick YANG
Author Information
1. Department of Orthopedic Surgery, Yonsei University College of Medicine, Seoul, Korea. qshin@yuhs.ac
- Publication Type:Original Article
- Keywords:
sacrum;
pelvic bone;
giant cell tumor;
arterial embolization
- MeSH:
Giant Cell Tumors*;
Giant Cells*;
Humans;
Medical Records;
Pelvic Bones;
Retrospective Studies;
Sacrum
- From:The Journal of the Korean Bone and Joint Tumor Society
2013;19(2):50-55
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The purpose of this study is to determine the usefulness of arterial embolization on sacral and pelvic giant cell tumor (GCT). MATERIALS AND METHODS: We retrospectively reviewed the medical records of 9 patients who had undergone serial arterial embolization between December 1996 and May 2008. We analyzed the clinical outcomes and therapeutic responsiveness of arterial embolization on sacral and pelvic GCT. RESULTS: Six of 9 cases showed progression of disease (PD) status, even if 5 cases showed PD status despite of additional treatments including surgery and radiation, implying that serial arterial embolization on sacral and pelvic GCT is not effective. Three of 9 cases showed stable disease (SD) or continuous disease free (CDF) status and we analyzed associated factors with these good responses for embolization by chi2 test. The number of feeding vessels under six (p=0.048) and the number of collateral arterial supply under three (p=0.048) in the first angiogram showed significant relationships with good response for embolization, while remaining tumor staining by contrast after the first embolization and repeated embolization times were not significant. CONCLUSION: Although serial arterial embolization is not an effective modality on sacral and pelvic giant cell tumors, it may be a pilot modality under narrow indication of tumors with poor vascularity at first angiogram.
