Doubts and strategies in the treatment of follicular lymphoma
10.3760/cma.j.issn.1009-9921.2012.06.002
- VernacularTitle:滤泡性淋巴瘤治疗中的疑惑和应对策略
- Author:
Huaqing WANG
- Publication Type:Journal Article
- Keywords:
Lymphoma,follicular;
,Asymptomtic diseases;
Recurrence;
Rituximab;
Stem cell transplantation;
maintenance treatment
- From:
Journal of Leukemia & Lymphoma
2012;21(6):325-329,334
- CountryChina
- Language:Chinese
-
Abstract:
In the past 5 years,the treatment paradigm for patients with follicular lymphoma(FL) has undergone significant changes,with the development of effective new agents that are now being used in the upfront,maintenance,and relapsed/refractory settings.Although these new therapies have led to improvements in patient outcomes,numerous questions remain regarding their optimal use in the treatment of the disease.In this article,the questions related to the timing of therapy for asymptomatic patients,strategies for treating advanced and relapsed/refractory disease,the safety and efficacy of rituximab maintenance and the evolving role of transplantation in the era of novel agents were responded.The latest data from clinical trials of investigational agents that are showing promise in FL were also discussed.
