Engraftment syndrome after allogeneic hematopoietic stem cell transplantation: a case report and literature review

VernacularTitle:HLA单倍体相合异基因造血干细胞移植后植入综合征一例并文献复习
Author: Feng NING ; Jingwen WANG ; Lei YANG ; Xin LI
Publication Type:Journal Article
Keywords: Hematopoictic stem cell transplantation; Engraftment syndrome
From: Journal of Leukemia & Lymphoma 2009;18(7):415-416,418
CountryChina
Language:Chinese
Abstract: Objective To study the engraftment syndrome (ES) and the possible etiology after haploidentical allognneic hematopoietic stem cell transplantation (al]o-HSCT). Methods The clinical manifestation, treatment and outcome of a chronic myeloid leukemia patient who after allo-HSCT were presented. Results The patient started to cough on day 2 after allo-HSCT, dry cough at beginning, white foam sputum, non-infectious fever, fluid retention, weight gain, transient encephalopathy on day 4. The clinical symptoms were improved after treatment with corticosteroids, in which ES was diagnosed. Conclusion ES is a series of clinical syndromes following transplantation which is different from acute graft versus host disease. It occurred after HSCT, and corticosteroids are often effective. Therefore early recognition and accurate diagnosis is very important.