Alteration and significance of coagulation function in patients with stage Ⅲ-Ⅳ non-Hodgkin lymphoma

VernacularTitle:Ⅲ、Ⅳ期非霍奇金淋巴瘤患者凝血功能变化的意义
Author: Yajun JIANG ; Jian GU ; Zhongqiang WANG ; Lianjun SHEN ; Hongxia WANG ; Lili KANG
Publication Type:Journal Article
Keywords: Lymphoma,non-Hodgkin; Coagulation function
From: Journal of Leukemia & Lymphoma 2009;18(7):419-420,423
CountryChina
Language:Chinese
Abstract: Objective To observe the alteration of coagulation function in the patients with stage Ⅲ～Ⅳ non-Hodgkin lymphoma and evaluate its clinical significance. Methods 62 patients with NHL and 20 healthy examiners were studied. The parameters of PT, APTT, TT and FIB in blood plasma were detected.Results The levels of APTT and FIB in NHL group were significantly higher than that in control group (P <0.05 and<0.01), and in stage Ⅲ and Ⅳ NHL groups both were significantly higher than that in control group and stage Ⅱ group (P< 0.05 and <0.01). The levels of FIB in ⅢB, ⅣA and ⅣB group were significantly higher than that in control group and ⅢA group (P<0.01), but there was no statistical significance among ⅢB, ⅣA and ⅣB group (P >0.05).Conclusion The NHL patients especially ⅢB～ⅣB patients usually accompany with abnormal coagulation function and hypercoagnlable states, and it' s necessary to monitor their coagulation function.