Salvia miltiorrhiza combined with dextran to prevent veno-occlusive disease after hematopoietic stem cell transplantation
10.3760/cma.j.issn.1009-9921.2009.08.009
- VernacularTitle:复方丹参联合低分子右旋糖酐预防造血干细胞移植后肝静脉闭塞病
- Author:
Liang XIAO
;
Zhiguo WANG
;
Yauling FAN
;
Bo CHEN
;
Qinghua TANG
;
Zhaomin ZHAN
;
Bolong ZHANG
;
Jun MA
- Publication Type:Journal Article
- Keywords:
FUFANG DANSHEN;
Dextran;
Hepatic veno-occlusive disease
- From:
Journal of Leukemia & Lymphoma
2009;18(8):469-470,472
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinic effect of the Salvia miltiorrhiza combined with dextran to prevent veno-occlusive disease after hematopoietic stem cell transplantation. Methods In the process of the pretreatment of the hematopoietic stem cell transplantation, patients were treated with salvia miltiorrhiza (20 ml/d), dextran(250 ml, twice a day) by venous transfusion and the drugs to protect the liver cell was used in the same time. When the count of platelet dropped to 30×109/L, salvia miltiorrhiza and dextranware stopped applying forever. Results Veno-occlusive disease and hemorrhage has not occurred during 85 times of the hematopoietic stem cell transplantation treated with salvia miltiorrhiza and dextran. Conclusion We conclude that the combined treatment with salvia miltiorrhiza and dextran is safe and effective to prevent veno-occlusive disease after hematopoietic stem cell transplantation.
