Research progress of Galectin-1 in the development of tumor
10.3760/cma.j.issn.1008-1372.2015.05.003
- VernacularTitle:Galectin-1与肿瘤发生发展的研究进展
- Author:
Xujun HE
;
Yingjie XIA
;
Zhengchuang LIU
;
Houquan TAO
;
Zaiyuan YE
- Publication Type:Journal Article
- Keywords:
Galectins/ME;
Neoplasms/ME;
Review
- From:
Journal of Chinese Physician
2015;17(5):648-651,657
- CountryChina
- Language:Chinese
-
Abstract:
Nowadays more and more biologists and immunologists focus on Galectin-1 due to the in -depth study of Galectins.As one of the important member of Galectins,Galectin-1 distributes widely,exists in a variety of tissues and cells,involves in cell adhesion,proliferation,apoptosis and inflammatory reaction,and results in a variety of physiological and pathological process.Recent studies have found that Galectin-1 expression in a variety of malignant tumor with a close relationship with tumor occurrence,invasion,development,anti-tumor immunity,and metastasis.It may be a potentially new target for cancer and inflammation therapies.This present paper reviews the current research about Galectin-1 and tumor progression.
