Clinicopathological observation on primary leiomyosarcoma of thyroid gland
10.3969/j.issn.1671-8348.2015.14.011
- VernacularTitle:甲状腺原发性平滑肌肉瘤临床病理观察
- Author:
Jue XIAO
;
Jin LI
;
Rong SONG
- Publication Type:Journal Article
- Keywords:
thyroid gland;
leiomyosarcoma;
immunohistochemistry;
pathological;
differential diagnosis
- From:
Chongqing Medicine
2015;(14):1902-1903,1905
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinicopathological features ,diagnosis and differential diagnosis of primary leiomyo‐sarcoma of the thyroid gland .Methods The pathological characteristics and immunohistochemical features in a case of primary leio‐myosarcoma of the thyroid gland were analyzed and the relevant literatures were reviewed .Results Grossly ,the mass measured 5 .5 cm × 4 .0 cm × 3 .5 cm ,gray and yellow in cut surface and partial hard quality .Histologically ,the tumor was composed of spin‐dle cells ,arranging in bundles with obvious dysplasia ,nuclear mitosis was easily found .The tumor infiltrated thyroid follicles and in‐vaded surrounding tissues .The immunohistochemical study showed that Vimentin ,SMA ,Caldesmon and Actin were positive ,and CK ,CK8 ,EMA ,TTF‐1 ,P53 and LCA were negative .Conclusion Primary leiomyosarcoma of thyroid gland is extremely rare ,its diagnosis should be combined with clinical and imageologic data ,histological characteristics and immunohistochemistry .
