Clinical significance of serum levels of procalcitonin,C-reactive protein and white blood cell count in children with infectious diseases
10.3969/j.issn.1673-4130.2015.12.013
- VernacularTitle:感染性疾病患儿血清降钙素原、CRP及WBC的变化及临床意义
- Author:
Meiqiong HUANG
;
Guangqing ZHANG
;
Jingjing GE
;
Lihan XU
;
Zhaobin YU
- Publication Type:Journal Article
- Keywords:
procalcitonin;
C-reactive protein;
white blood cell count;
infectious diseases
- From:
International Journal of Laboratory Medicine
2015;(12):1670-1671,1673
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the diagnostic value of serum procalcitonin ,C‐reactive protein and white blood cell count in children with different diseases .Methods Retrospective analysis 94 cases of pathogenic infectious children from June 2013 to May 2014 in our hospital ,according to the results of pathogen detection was divided into bacterial infection 36 cases ,mycoplasma infec‐tion group 28 cases ,30 cases of viral infection ,detection and analysis serum PCT ,CRP and WBC levels .Results Bacterial infection group serum PCT ,CRP and WBC were (2 .41 ± 0 .94)ng/mL ,(47 .91 ± 18 .26)mg/L and (13 .18 ± 6 .03) × 109/L ,significantly higher than the mycoplasma infection and viral infection group (F=133 .4 ,F=60 .1 ,F=8 .5 ,P<0 .05);diagnosis of bacterial in‐fections ,PCT sensitivity and specificity were 92 .11% and 91 .05% ,positive and negative predictive value of 89 .84 % and 94 .01%were significantly higher than CPR and WBC ,Mycoplasma infection as the control group ,PCT ,CRP and WBC in the diagnosis of bacterial infections ,the area of under the ROC curves were 0 .816 ,0 .728 and 0 .614 ,respectively .Conclusion Serum PCT for the i‐dentification of bacterial infections has a high diagnostic value ,worth generalizing and applying .
