Real-time Three-dimensional Speckle Tracking Imaging in Evaluating Global Left Ventricular Systolic Function in Patients with Type 2 Diabetes and Poor Blood Glucose Control
10.3969/j.issn.1005-5185.2015.06.010
- VernacularTitle:实时三维斑点追踪成像评价2型糖尿病血糖控制不良患者左心室整体收缩功能
- Author:
Lei GAO
;
Xin LIU
;
Shuqin GUO
;
Chunqing LI
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus,type 2;
Blood glucose;
Echocardiography,three-dimensional;
Speckle tracking imaging;
Ventricular function,left
- From:
Chinese Journal of Medical Imaging
2015;(6):439-443,448
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To evaluate three-dimensional strain changes of the left ventricle in patients with type 2 diabetes and poor blood glucose control using real-time three-dimensional speckle tracking imaging (RT3D-STI), and to assess the correlation between three-dimensional strains and hemoglobin A1C (HbA1c). Materials and Methods Sixty-nine patients with type 2 diabetes and forty-two control subjects were recruited in this study. The patients were divided into DM1 group (patients with well blood glucose control, HbA1c<6.5%) and DM2 group (patients with poor blood glucose control, HbA1c ≥ 6.5%) according to the glycosylated hemoglobin level. Parameters including global longitudinal strain (GLS), global circumferential strain (GCS), global radial strain (GRS), global area strain (GAS), left ventricular ejection fraction (LVEF), left ventricular end-diastolic volume (LVEDV), left ventricular end-systolic volume (LVESV) and left ventricular mass (LVM) were obtained from cardiac apex full volume images by using RT3D-STI. The parameters of three groups were compared, and the correlation between the cardiac parameters and HbA1c were analyzed. Results The GAS, GLS, GCS, GRS, LVEDV, LVESV, LVM and LVEF showed no statistic difference between DM1 group and control group (P>0.05). LVM of DM2 group was higher than that in control group (P<0.01), but GAS and GLS of DM2 group were lower than those in control group (P<0.05). LVM of DM2 group was higher than that in DM1 group (P<0.01), but GAS and GLS of DM2 group were lower than those in DM1 group (P<0.01). HbA1c was negative correlated with GAS and GLS (r= - 0.773 and 0.465, P<0.01). Conclusion The reduced GAS and GLS of the patients with type 2 diabetes and poor blood glucose control may indicate damaged myocardial function.
