Effects of low frequency electrical stimulation on blood hormone levels in different animals

VernacularTitle:低频电刺激对不同动物血内激素水平的影响
Author: Farong YU ; Xiaoxi NING ; Wen YU ; Mingren XIE ; Xiuzhen LIAN ; Denglou LI ; Shishuang ZHANG
Publication Type:Journal Article
Keywords: Low frequency electrical stimulation; Hormone; Stress; Chinese tree shrews; Rats; Mice
From: Acta Laboratorium Animalis Scientia Sinica 2015;(3):245-248,255
CountryChina
Language:Chinese
Abstract: Objective To study the effect of low frequency electrical stimulation on blood hormone levels in differ -ent animals.Methods At 12 h, 24 h and 36 h after low frequency electrical stimulation to Chinese tree shrews , Wistar rats, and BALB/c mice, respectively, the blood noradrenaline (NA) and endothelin (ET) levels were determined by ra-dioimmunoassay ( RIA) .Results The blood NA and ET levels of electrical stimulation group were significantly higher than that in the control group (P <0.01).At 24 h after reserpine treatment, the same electrical stimulation was given. The NA, ET levels were significantly decreased compared with that in the electrical stimulation group (P<0.05 to 0.01). Different animals responded to the same electric stimulus differently , following the order of Chinese tree shrews >Wistar rats >BALB/c mice.Conclusions Low frequency electrical stimulation can promote the release of noradrenaline and en -dothelin in Chinese tree shrews , Wistar rats and BALB/c mice.Reserpine can reduce the stress induced by low frequency electric stimulation to the body .