Comparative analysis of radiotherapy alone,thermoradiotherapy and radiotherapy and chemotherapy of esophageal cancer effect
- VernacularTitle:单纯放疗、热放疗与放化疗治疗食管癌的效果比较
- Author:
Yanfeng LIU
;
Hui GUO
;
Shanfeng SU
- Publication Type:Journal Article
- Keywords:
Radiation therapy;
Chemotherapy;
Antitumor chemotherapy regimen,Combined;
Esophageal neoplasm
- From:
Chinese Journal of Primary Medicine and Pharmacy
2015;(15):2250-2252,2253
- CountryChina
- Language:Chinese
-
Abstract:
Objective To comparative analysis the effect of radiotherapy,thermoradiotherapy and chemora-diotherapy on esophageal cancer.Methods 120 patients with esophageal carcinoma were selected and randomly divided into the radiotherapy group,thermoradiotherapy groupand chemoradiotherapy group by digital table method, with 40 cases in each group,which were treated with radiotherapy alone,thermoradiotherapy alone and radiotherapy combine with chemotherapy respectively.The effects of treatment of the three groups were compared.Results The main toxic reaction in the three groups during the treatment for adverse reaction were digestive system reaction,hema-tologic toxicities and radioactive esophagitis.The incidence of toxic reaction of the three groups were not statistically significant(P >0.05).Total response rate of simple radiotherapy group,the thermal radiation group,chemoradiothera-py group were 52.5%,75.0% and 85.0%.,The total remission rate of chemotherapy group was higher than those of the radiotherapy group and the thermal radiation group(χ2 =5.218,3.857,all P <0.05).Conclusion The different treatment methods of esophageal cancer can obtain certain curative effect,but there are some adverse reactions.Among different treatment methods,radiotherapy and chemotherapy in the treatment of esophageal carcinoma can get better effect than the radiotherapy and chemoradiotherapy.