The research of the analgesic effects by acupuncture at jiaji points in rat of incisional pain
10.3969/j.issn.1671-8348.2015.18.006
- VernacularTitle:针刺夹脊穴对切口痛大鼠的镇痛效应
- Author:
Xing ZHOU
;
Qiang QU
- Publication Type:Journal Article
- Keywords:
acupuncture analgesia;
points EX-B2;
rat,inbred strains
- From:
Chongqing Medicine
2015;(18):2464-2466,2470
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of the application of acupuncture Jiaji points and continuous acupoints infusion of analgesic drugs at Jiajji in the treatment of postoperative pain on rat behavior through the establishment of a rat model of incisional pain .Methods 60 healthy male SD rats ,were randomly divided into sham control group ,PI group ,CSI group ,EA group and CAI group ,12 in each group .Plantar incision pain model in rats was established according to the method of Brennan ,rats in 5 groups at preoperative 1 h and 6 ,24 ,48 h after operation ,mechanical withdrawal threshold(MWT) and thermal withdrawal latency(TWL) were evaluated .Results Changes in MWT :5 groups of rats with experimental basis of mechanical withdrawal threshold values showed no significant difference among them ;comparison of the mechanical withdrawal threshold in the sham control group at each time point showed no significant difference(P>0 .05);when compared with sham control group ,MWT in PI group ,CSI group ,EA group and CAI group decreased significantly at 6 ,24 ,48 h after operation (P<0 .05);when compared with PI group ,MWT in CSI group ,EA group and CAI group increased significantly at 6 ,24 ,48 h after operation(P<0 .05);when compared with CSI group and EA group ,MWT in CAI group increased significantly at 6 ,24 ,48 h after operation (P<0 .05) .Changes of TWL :when compared with the sham control group ,TWL decreased significantly in PI group at 6 ,24 ,48 h after operation (P< 0 .05);when compared with the sham group ,TWL in CSI group ,EA group ,CAI group increased significantly at 6 ,24 ,48 h after operation (P<0 .05);when compared with CSI group and EA group ,TWL in CAI group increased significantly at 6 ,24 ,48 h after operation (P<0 .05) . Conclusion Electroacupuncture and continuous acupoint infusion of analgesic drugs at Jiaji could produce obvious analgesic effect , the analgesia effect of continuous acupoint infusion at Jiaji is better than subcutaneous analgesia .
