Relationship between absolute monocyte/lymphocyte count and prognosis in low-risk patients with aggressive B cell lymphoma
10.3969/j.issn.1671-8348.2015.16.018
- VernacularTitle:AMC及 ALC与侵袭性B细胞淋巴瘤低危患者的预后关系分析
- Author:
Daiying HE
;
Zhibing LUO
;
Jing LI
;
Chen WANG
- Publication Type:Journal Article
- Keywords:
monocyte;
lymphocyte;
lymphoma,B cell;
low-risk;
prognosis
- From:
Chongqing Medicine
2015;(16):2212-2213,2216
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prognostic significance of peripheral blood absolute monocyte/lymphocyte count in low‐risk patients with aggressive B cell lymphoma .Methods Retrospective study was performed in 42 low‐risk patients with ag‐gressive B cell lymphoma approved by histology between 2003 to 2013 .Peripheral blood absolute monocyte count (AMC) ,absolute lymphocyte count (ALC) ,lymphocyte/monocyte(LMR) and the some other clinical characters were estimated .Results The best absolute monocyte/lymphocyte count cut‐offs respectively were 475/mm3 and 1 005/mm3 ,analyzed by receiver operating character‐istic curve .AMC≥475/mm3 and ALC<1 005/mm3 were found to be independent predictors of progress free survival (RR=4 .271 , 3 .023 ;P= 0 .01 ,0 .39);AMC≥475/mm3 was found to be independent predictors of 5‐year overall survival (RR= 4 .680;P<0 .0001) in low‐risk patients with aggressive B cell lymphoma .Conclusion Higher AMC and/or lower ALC are poor prognosis fac‐tors .AMC and ALC may be important prognostic factors of low‐risk patients with aggressive B cell lymphoma .
