Diagnosis and differential diagnosis of pulmonary marginal zone B cell lymphoma of mucosa associated lymphoid tissue
10.3760/cma.j.issn.1009-9921.2013.11.009
- VernacularTitle:肺黏膜相关淋巴瘤的诊断与鉴别诊断
- Author:
Dongguan WANG
;
Xiaoqiu ZHOU
;
Linlin WANG
;
Xiyin SUN
;
Qing LI
;
Xingong LI
- Publication Type:Journal Article
- Keywords:
Lymphoma,mucosa-associated lymphoid tissue;
Lung;
Diagnosis,differential
- From:
Journal of Leukemia & Lymphoma
2013;22(11):671-673,677
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical,imaging and pathological characteristics and diagnostic methods of pulmonary mucosa-associated lymphoid tissue-derived lymphoma (MALToma),and differentiate from three kinds of pulmonary lymphatic hyperplasia.Methods Medical history,imaging and pathological examination of three cases of pulmonary MALToma were introduced in detail.And differentiated from lymphocytic pseudolymphoma (nodular lymphoid hyperplasia),follicular bronchiolitis and lymphocytic interstitial pneumonia.Results The clinical manifestations and imaging examination of pulmonary MALToma had no special and were not easy to differentiate from cancer.Histopathologically,widened marginal zones encircled one or more germinal centers.The neoplastic lymphocytes invaded germinal center and bronchiole resulting in follicle colonization and lymphoepithelial lesions.Conclusion Pulmonary MALToma is a rare low grade malignant tumor.Histopathology is the key method to diagnosis,while clinical manifestations and imaging examination have no special symptoms at diagnosis.MALToma is differed from pulmonary lymphatic hyperplasia in widened marginal zone encircled one or more germinal centers,follicular colonization,lymphoepithelial lesions,cell types between follicular.
