Clinical study of pancreatic lymphoma presenting as acute pancreatitis

VernacularTitle:以急性胰腺炎为首发症状的胰腺淋巴瘤临床特征研究
Author: Shuang QU ; Lisheng LIAO ; Yun LIN ; Biyun CHEN ; Weimin CHEN
Publication Type:Journal Article
Keywords: Pancreatitis; Lymphoma,pancreatic
From: Journal of Leukemia & Lymphoma 2013;22(11):665-667,670
CountryChina
Language:Chinese
Abstract: Objective To analyze the clinical features and diagnosis-treatment of pancreatic lymphoma presenting as acute pancreatitis.Methods The clinical records of 7 patients including laboratory findings were retrospectively reviewed.Some related medical literatures were reviewed.Results Seven patients presented acute abdominal pain.Laboratory findings revealed significant increase of serum amylase and lipase levels.CT scan of the abdomen or PET-CT showed a diffuse swelling of the pancreas or masses in the body or tail.Extrapancreatic spread such as bone,bone marrow,spleen infiltrate was found out in 5 patients.Of the 7 patients,6 were diagnosed as the diffuse large B-cell lymphoma,1 as the anaplastic large cell lymphoma.Six patients underwent systematic chemotherapy.Two died and the others received complete or part remission.Conclusion Pancreatic lymphoma is uncommon and represents a rare cause of acute pancreatitis.It needs to be confirmed by histopathologic examination.The standard treatment is not only for acute pancreatitis,but also for NHL including CHOP or CHOP-like chemotherapy.