Clinical analysis of 118 cases adverse reactions of anti-hypertension drug
10.3760/cma.j.issn.1008-6706.2015.s1.008
- VernacularTitle:抗高血压药物不良反应118例报告
- Author:
Chunmei GU
;
Jiaping QIU
- Publication Type:Journal Article
- Keywords:
Antihypertensive Agents;
Adverse Drug Reaction Reporting Systems;
Drug Toxicity
- From:
Chinese Journal of Primary Medicine and Pharmacy
2015;(z1):21-22,23
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the significance of the hypertension management in root level communitiesand improve patients′treatment compliance and therapeutic effects by summarizing and analyzing adverse reactionscaused by antihypertensive drugs.Methods Retrospectively summarize clinical data of 118 hypertension patients andstatistically analyzed relevant data in a classified manner.Results 43 cases of 118 patients were male,accounting for36.4%,and 75 cases were female accounting for 63.6%.Female patients were more than male patients and the ratioof male patients to female ones is 1:1.74.Patients from 50 to 69 years old were significantly more than those of otherages and account for 62.2%.The incidence rates of adverse reactions caused by calcium channel blockers(CCB),Angiotensin Ⅱ receptor antagonist(ARB),ACEI,compound preparation,diuretic and beta receptor blockers are54.1%,21.2%,13.6%,9.3%,0.9% and 0.9%.Main clinical adverse reactions were edema of lower extremity,flush,headache,lack of power,cough,etc.Conclusion The prevalence of the hypertension in females is higher thanthat in males,the prevalence of the hypertension in patients from 50 to 69 is higher than that in patients of other ages,adverse reactions caused by antihypertensive drugs are associated with the gender and age of the patients and varietyof the drugs and such drugs should be selected on a reasonable basis during hypertension treatment.
