Research progress of salvianolic acid B in cardiovascular diseases
10.3969/j.issn.1001-1978.2015.04.002
- VernacularTitle:丹酚酸B在心血管疾病中药理作用研究进展
- Author:
Chao LIN
;
Zhaoguo LIU
;
Xing QIAN
;
Yuan YAO
;
Bin XU
;
Huimin BIAN
- Publication Type:Journal Article
- Keywords:
salvianolic acid B;
myocardial infarction;
ischemia-reperfusion;
cardiomyocyte hypertrophy;
molecular mechanisms;
therapeutic strategies
- From:
Chinese Pharmacological Bulletin
2015;(4):449-451,452
- CountryChina
- Language:Chinese
-
Abstract:
Cardiovascular disease is a serious threat to human health and quality of life ,and it has become the leading cause of death in human.Thus,looking for effective drugs to reduce the mortality and morbidity of such a disease has become a problem to be solved.Due to its good efficacy of activating blood circula-tion and dissipating blood stasis,salvia miltiorrhiza has been widely used in the treatment of cardiovascular disease and ob-tained a good curative effect.Salvianolic acid B is one of the main water-soluble components of salvia miltiorrhiza extract and studies have shown that salvianolic acid B possesses many biolog-ical activities,which not only has a good protective effect on my-ocardial infarction,but could significantly alleviate myocardial ischemia-reperfusion injury.This article reviews the research progress of salvianolic acid B in cardiovascular diseases,and al-so includes discussion about the mechanisms of salvianolic acid B in the regulation of cardiovascular diseases,which may provide references for follow-up research and clinical treatment.
