Diagnostic significance of PCT for neonatal sepsis
10.3969/j.issn.1673-4130.2015.07.021
- VernacularTitle:降钙素原对新生儿脓毒症的诊断意义
- Author:
Weizhou QIAO
;
Tingting YANG
;
Yunyun YANG
- Publication Type:Journal Article
- Keywords:
procalcitonin;
C-reactive protein;
white blood cell count;
neonatal sepsis
- From:
International Journal of Laboratory Medicine
2015;(7):913-914,917
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the special diagnostic superiority of PCT test over CRP and WBC count test for neonatal sepsis .Methods 46 newborn inpatients diagnosed neonatal sepsis in the neonatal department of Dalian Central Hospital from Janu‐ary 2013 to January 2014 and contemporaneous 50 uninfected neonatal inpatients as control group were collected .The PCT and CRP concentrations and WBC count were simultaneously measured at admission .Results The WBC count had no statistical difference between the two groups ,but the PCT and CRP detection showed the statistical difference between the two groups (P<0 .01) ,the sensitivity of PCT test was 87% ,which was significantly higher than 63% of CRP test ,but the specificity of PCT test was 87% , which was slightly lower than 90% of CRP test .The Youden index of PCT test was obviously higher than that of CRP test and WBC count .Conclusion PCT is superior to CRP and WBC count in diagnosing neonatal sepsis .