Analysis on results of HBsAg weakly positive and both HBsAg and HBsAb simultaneously positive
10.3969/j.issn.1673-4130.2015.07.028
- VernacularTitle:HBsA g弱阳性及 HBsA g和 HBsA b同时阳性的结果分析
- Author:
Fang HUANG
;
Yadong LIU
;
Caixia ZHENG
;
Erli JI
;
Lili ZHAO
- Publication Type:Journal Article
- Keywords:
hepatitis B;
enzyme-linked immunosorbent assay;
electrochemiluminescence immunoassay
- From:
International Journal of Laboratory Medicine
2015;(7):930-931,933
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the results of HBsAg weakly positive and both HBsAg and HBsAb simultaneously positive in 5 items of hepatitis B detected by ELISA .Methods 115 cases of HBsAg weakly positive and 95 cases of both HBsAg and HBsAb simultaneously positive were screened out from 35 280 cases of 5 items detection results of hepatitis B .210 screened samples were performed the electrochemiluminescence immunoassay (ECLIA) quantitation .Results 115 cases of HBsAg weakly positive were re‐detected by using ECLIA ,90 cases had the consistent results with the coincidence rate of 78 .3% .After ECLIA re‐detection in 95 cases of HBsAg and HBsAb double positive results ,11 cases had the consistent results with the coincidence rate of 11 .6% .Conclu‐sion The results of HBsAg weakly positive and both HBsAg and HBsAb double positive in 5 items of hepatitis B detected by ELISA must be cautious .In the detection results of HBsAg weakly positive ,the majority are the samples of HBsAg ,HBeAb and HBcAb positive and HBsAg and HBcAb positive .The results of HBsAg and HBsAb simultaneously positive have poor reliability , which should be careful to issue the detection reports .