Relationship between positive rate of EBV and HCMV testing with patients′age in 179 cases of leukemia
10.3969/j.issn.1673-4130.2015.07.009
- VernacularTitle:179例血液病患者EBV和HCMV核酸检测阳性率与患者年龄的关系
- Author:
Changguo CHEN
;
Jianwei GUO
;
Qing DU
;
Wenjun LI
;
Min LIU
;
Qiangyuan ZHAO
- Publication Type:Journal Article
- Keywords:
epstain-barr virus;
human cytomegalovirus;
leukemia;
gene testing
- From:
International Journal of Laboratory Medicine
2015;(7):885-886,888
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the relationship between the positive rate of Epstain‐Barr virus (EBV) and human cyto‐megalovirus (HCMV) nucleic acid detection with the age in the patients with aplastic anemia ,acute lymphoblastic leukemia and my‐eloid leukemia .Methods The patients clinically diagnosed as aplastic anemia ,acute lymphoblastic leukemia ,and myeloid leukemia after bone marrow puncture in the Navy General Hospital from January 2012 to December 2013were collected as the research sub‐jects .the nucleic acid test kit from DAAN Gene Company was adopted for conducting the EBV and HCMV nucleic acid testing and analyzing the relationship between the positive rate of the EBV and HCMV infection with the patient′s age .Results There were different testing positive rate among 3 kinds of hematonosis .As a whole ,the positive rate of HCMV was lower than that of EBV (15 .8% vs .43 .7% ) .The EBV nucleic acid detection positive rate had statistically significant difference among different ages of pa‐tients with aplastic anemia and myeloid leukemia .(P< 0 .01) .Conclusion For children patients with aplastic anemia disease and myeloid leukemia ,more attention should be paid to monitoring of EBV and HCM V nucleic acid .
